Limited mediated telepathy

A rat was implanted with a 32-unit microelectrode cortical array in either M1 or S1. The rat was then trained to choose between two alternatives based on external stimuli.

Meanwhile, another rat was implanted with 6 stimulating electrodes in the same area as the first rat. It was trained to choose between the same two alternatives based on a stimulation pattern conveyed via the electrodes.

Then the signals recorded from the first rat’s brain were processed ald sent into the second rat’s brain. Both rats were trained together and both were rewarded when both made the right choice. The second rat learned to make the same choice as the first rat 60% of the time.

Miguel Pais-Vieira, Mikhail Lebedev, Carolina Kunicki, Jing Wang, Miguel A. L. Nicolelis. A Brain-to-Brain Interface for Real-Time Sharing of Sensorimotor Information. Scientific Reports 3, Article number: 1319. Received 20 December 2012.

Mobile phone increases brain glucose metabolism near phone antenna

This study claims that glucose metabolism in the brain goes up near a cellphone antenna. At first blush this may appear to conflict with other studies that claim that cellphones don’t cause cancer, but this can be resolved by supposing that cell phones don’t cause cancer, but affect the brain in other ways. As Volkow notes at the end of the Nytimes article, this may lead to the discovery of a mechanism for brain stimulation. Right now they don’t know what the mechanism is by which the electromagnetic field is causing the glucose metabolism. If neuronal firing is being altered, and if the bandwidth turns out to be sufficiently high (i.e. if the stimulation can be made sufficiently precise), this could eventually lead to a wireless brain-machine interface/neural prosthetic.

PET scans showing effect

Nora D. Volkow, Dardo Tomasi, Gene-Jack Wang, Paul Vaska, Joanna S. Fowler, Frank Telang, Dave Alexoff, Jean Logan, Christopher Wong. Effects of Cell Phone Radiofrequency Signal Exposure on Brain Glucose Metabolism. JAMA. 2011;305(8):808-813.

Summary in NYtimes: Cellphone Use Tied to Brain Changes

Transcranial Pulsed Ultrasound Stimulates Intact Brain Circuits

Yusuf Tufail, Alexei Matyushov, Nathan Baldwin, Monica L. Tauchmann, Joseph Georges, Anna Yoshihiro, Stephen I. Helms Tillery, William J. Tyler. Transcranial Pulsed Ultrasound Stimulates Intact Brain Circuits. Neuron, Volume 66, Issue 5, 681-694, 10 June 2010.

In motor cortex, ultrasound-stimulated neuronal activity was sufficient to evoke motor behaviors. Deeper in subcortical circuits, we used targeted transcranial ultrasound to stimulate neuronal activity and synchronous oscillations in the intact hippocampus. We found that ultrasound triggers TTX-sensitive neuronal activity in the absence of a rise in brain temperature (<0.01°C). Here, we also report that transcranial pulsed ultrasound for intact brain circuit stimulation has a lateral spatial resolution of approximately 2 mm and does not require exogenous factors or surgical invasion.

Conference on Neuroprosthetic Devices

The First International Conference on Neuroprosthetic Devices will take place at National Chiao Tung University, Hsinchu, Taiwan on March 19th and 20th, 2009. The mission of this newly founded conference is to foster West-East interaction and collaboration in the rapidly advancing clinical use of neuroprosthetics. The specific aim of the first conference is to expose unique technological and neurological research opportunities in Taiwan. National Chaio Tung University is one of the best universities in Taiwan and is located right next to the world-famous HsinChu Science Park hosting hundreds of biotechnology, semiconductor, and electronics companies.

The conference sessions will cover several key areas in the neuroprosthetic development, such as deep brain stimulation for treatment of Parkinson’s disease and epilepsy, devices for restoring hearing and overcoming muscle paralysis, microelectrode biocompatibility, and novel microelectrode technologies. For detailed conference program and registration information, please visit

Your Brain Is A Cartographer

The concept that the brain holds maps of the surface of the body in the primary sensory and motor cortex is a fascinating but well known fact to the field of neuroscience since the early work of Wilder Penfield. What is less broadly appreciated is the concept of “peripersonal space”. A new book by Sandra and Matthew Blakeslee describes peripersonal space in the following way:

The maps that encode your physical body are connected directly, immediately, personally to a map of every point in that space and also map out your potential to perform actions in that space. Your self does not end where your flesh ends, but suffuses and blends with the world, including other beings. […] Your brain also faithfully maps the space beyond your body when you enter it using tools. Take hold of a long stick and tap it on the ground. As far as your brain is concerned, your hand now extends to the tip of that stick. […] Moreover, this annexed peripersonal space is not static, like an aura. It is elastic. […] It morphs every time you put on or take off clothes, wear skis or scuba gear, or wield any tool. […] When you eat with a knife and fork, your peripersonal space grows to envelop them. Brain cells that normally represent space no farther out than your fingertips expand their fields of awareness outward, along the length of each utensil, making them part of you.

What I appreciate about this, besides the stretchy comic book characters that it makes me think about, is that it provides a powerful perspective to begin piecing together a mass of disparate neuroscience data, which the Blakeslee’s capitalize on.

Continue reading

Human 2.0: New Minds, New Bodies, New Identites

The MIT Media Lab is holding a conference on May 9th, “Human 2.0: New Minds, New Bodies, New Identites” which will launch a number of new initiatives centered around the goal of inventing a better future via direct engineering of the human. Amongst these things will be the initiation of the MIT Center for Human Augmentation, and the launch of a number of novel applied Neurotechnology Projects.

Guest speakers on May 9th will include MIT professors (Roz Picard, Hugh Herr, myself, etc.) and many acclaimed speakers such as Oliver Sacks and John Donoghue. Registration may be close to being full, but it will be webcast.

More information at:

— posted by Ed