Technique named 'clarity' makes chunks of dead brain transparent, allowing fluorescent labeling

This technique takes a dead brain and permeates it with a transparent hydrogel matrix to keep proteins and nucleic acids in place. Then it removes the lipids. I guess the lipids are all that makes the brain opaque. At this point the brain is transparent but maintains its original structure so you can still label the proteins and nucleic acids.


http://www.hhmi.org/news/deisseroth20130410.html

Neuroscience as a new national priority

President Obama: “Now, it’s time to get to work.”

NYT article: http://www.nytimes.com/2013/04/02/science/obama-to-unveil-initiative-to-map-the-human-brain.html

 

http://www.whitehouse.gov/sites/default/modules/wh_multimedia/EOP_OVP_player.swf

UCSB/KITP Emerging Techniques in Neuroscience videos

Friend of the blog Jacob Robinson (who himself is pioneering impressive new techniques with nanowires for neural recording) writes:

While we’re all distributing scientific resources, I thought I’d point out that the KITP has a wonderful program on Emerging Techniques in Neuroscience, currently underway at UCSB. They have a great lineup of speakers with some overlap with the Allen Institute program. Videos of the talks are being posted online here.

So many good videos from good neuroscientists (including Chuck Stevens, John Hopfield, Clay Reid, Jeff Magee, Guoqiang Bi, and many more)… it’s going to take me a while to get through these. Enjoy!